AUTOLOGER FIBRINKLEBER

The Vivostat® system

The uniqueness of the Vivostat® system is a patented biotechnological process that enables reliable and reproducible preparation of autologous Fibrin Sealant or Platelet Rich Fibrin (PRF®) without using cryoprecipitation and without the need for a separate thrombin component.

The fully automated Vivostat® system consists of three components:

The Processor Unit
The Processor Unit is used to process the patient’s blood and prepare the Vivostat® Fibrin Sealant or Vivostat PRF® solution.

The Applicator Unit
The Applicator Unit controls the delivery of the Vivostat® solution to the site of treatment.

The Disposable Set
The single-use set contains all components needed for preparation and application of Vivostat® Fibrin Sealant or Vivostat PRF®. It is available with a range of application devices each optimised for different types of applications.

Vivostat Autologous Fibrin Sealant

For many years specialists have prepared autologous fibrin sealant based on thrombin and fibrinogen. The process is complicated, labour intensive and time consuming. With the Vivostat® system this process becomes fast and uncomplicated.

The uniqueness of the Vivostat® system is a novel patented biotechnological process that enables reliable and reproducible preparation of autologous fibrin sealant and related products without using cryoprecipitation and without the need for a separate thrombin component. Furthermore, Vivostat® Fibrin Sealant does not contain any bovine components and is completely aprotinin-free.

It is designed to provide the best possible solution for many different settings independent of whether it is used in the surgical area or centrally in e.g. the transfusion centre or the blood bank. The straightforward and intuitive operation means that there is no need for specially trained personnel.

Vivostat PRF® (Platelet Rich Fibrin)

Platelets and growth factors have been used for many years to help regenerate tissue and stimulate bone formation in e.g. orthopaedic surgery.

The thrombocyte solution used in these cases has traditionally been supplied by the blood bank.

Recently, a number of commercial products have entered the market with simpler and smaller devices that are still based on the same centrifugation technology. Most products still require sterile handling and have shortcomings in both the biophysical properties and the delivery system.

Vivostat has solved these problems by leveraging the revolutionary technology used in the Vivostat® system for the preparation and application of autologous fibrin sealant. By combining a fibrin sealant solution with a platelet concentrate, it is possible
to have a carrier, a controlled release and a medium for vascular ingrowth
– all in one product, Vivostat PRF® (Platelet Rich Fibrin).

The Vivostat® Co-Delivery system

Vivostat has developed the revolutionary Co-Delivery system that makes it possible to co-deliver a desired substance1 (drugs, stem cells etc.) with Vivostat® Fibrin Sealant or Vivostat PRF® (Platelet Rich Fibrin).

Vast opportunities

The opportunities with the Vivostat® Co-Delivery system are vast and the system allows the surgeon to apply a selected substance easily and effectively. Furthermore, it may be possible to reduce the total cost of a procedure by using the Vivostat® Co-Delivery system.

Options for Co-Delivery include:

Drugs
Antibiotics
Chemotherapeutics
Pain medications

Stem cells
Bone marrow derived
Adipose tissue derived